OK This is a shameless plug, but at least it's for a free Linux OS.
There are two versions of the iso, one includes "alt" in its title. Use the alt if your computer has an nforce2 chipset or if you are loading onto a laptop.
I've posted a couple of issues on this site in the announcements page, but for the vast majority of people it will "just work".
The real beauty of this distro is what it does out of the box. Eg, go to the bbc site and listed to the radio or play a video clip. Everything you need is already integrated into Firefox. All the mplayer codecs are loaded, the only things you really need from Synaptic are libcss and libdvdcss to play encrypted DVDs and you have a great multimedia machine.
The old Mandrake Control Centre has had a major makeover and the new PCLinuxOS Control Centre is far superior.
This is primarily a "Home User" distro though it can be adapted for any situation, all the software missing from the disk is at the repositories. Where it really stars is as a system to impress potential converts who think there is no alternative to making Bill rich!